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Health & Medicine - General

Delaying aging by inhibiting mitochondrial respiration

http://ouroboros.wordpress.com/2009/04/29/2339
Scanned by: mycophage over 2 years ago
The CLK-1 ("clock") pathway is a major conserved regulator of longevity: in organisms as diverse as mice and worms, mutations in the CLK-1 gene delay development and extend the lifespan. A new study from the Kenyon lab demonstrates that CLK-1 mutations act by inhibiting mitochondrial respiration, probably by blocking the producing of the essential mitochondrial cofactor ubiquinone (coenzyme Q).
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Type: Discovery  |  Also: |
  Tags
aging, clk1, mitochondria, ubiquinone

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